R&d Specialist Position for Support Within The

Il y a 3 mois

Luxembourg Université du Luxembourg Temps plein

The **Luxembourg Centre for Systems Biomedicine (LCSB)** is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and _in silico_. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors.

The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary and together we contribute to science and society.
- and intercellular mitochondrial signaling to these processes. For more information, please visit our website.

**Your Role...**:
You will be responsible for carrying out LC- and GC-based experiments in several research projects, which deal with the role of cellular metabolism in different iPSC-derived model systems of genetic PD. Moreover, you will be involved in cell culture maintenance and differentiation work within the framework of these projects.

To do so, you will have the following tasks and accountabilities:

- Support of cell culture activities (cell lines, primary cells, iPSC maintenance and differentiation)
- Standard molecular biology (Bradford, ELISA, Western blotting, immunocytochemistry) and mitochondrial function (Seahorse technology, colorimetric dyes, enzyme kinetics with spectrophotometry etc.) assays
- Real-time PCR, sequencing, cloning of plasmids and viral constructs
- Contribution to general laboratory organization (ordering, overseeing of stocks, storage, preparation of solutions etc.)

**What we expect from you**:

- Master’s degree in analytical chemistry, biochemistry, molecular biology, or another similar life science-related discipline
- Strong background in metabolic biochemistry, enzymology, and molecular biology
- Experience with cell culture, ideally with iPSC-derived cellular models
- Experience in mass spectrometry, preferably in a metabolomics setting
- Keen interest in investigating the molecular basis of neurodegenerative and neurometabolic diseases
- Strong motivation to contribute specific parts to larger projects
- Computational skills, including programming, will be considered as an important asset
- Solid bioinformatic and biostatistics skills
- Excellent organizational and management skills
- Excellent communication skills
- Fluency in oral and written English is essential

**Here’s what awaits you at the LCSB...**:

- **Excellent work environment** with state-of-the-art infrastructure, laboratory and administrative support
- **Truly connected. **We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab - the Scienteens Lab - to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science
- **Be part of a multicultural team. **At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more

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