R&d Specialist for Mfn Group

The **Luxembourg Centre for Systems Biomedicine (LCSB)** is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and _in silico_. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors.

The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary and together we contribute to science and society.

The University of Luxembourg has the following vacancy at the Luxembourg Centre for Systems Biomedicine (LCSB) - Molecular & Functional Neurobiology group**:Research & Development Specialist**
- and intercellular mitochondrial signaling to these processes. For more information, please visit our website.

The R&D specialist will support the implementation of various projects, including “CAMeSyn”, which explores the metabolic dependencies of neurons and astrocytes in Parkinson’s disease, and “ProtectMove II”, in which we investigate the crosstalk between environment and genetics in the pathogenesis of PD.

**Your Role...**:

- Generation/maintenance of induced pluripotent stem cells and subsequent differentiation into neurons, microglia and astrocytes
- Study of cellular intermediary metabolism (LC- and GC-based methods)
- Assessment of cellular and mitochondrial function using advanced imaging techniques and molecular biology methods (including RNA-seq)
- Data analysis, data interpretation and reporting of results
- Participate in knowledge dissemination activities through the preparation of scientific publications or presentations in scientific venues
- Participate in teaching activities (seminars and practicals)
- Support and tutoring of activity of students

**What we expect from you**:

- MSc in Life Sciences, Neurosciences, Molecular Biology or related field with solid lab experience (+5 years)
- Strong interest in interdisciplinary research and cellular models of neurodegeneration
- Proven experience (+5 years) in human induced pluripotent stem cell technologies, with solid knowledge in neuronal and glial differentiation protocols
- Good command of molecular biology methods
- Experience in RNA-seq analysis is considered an advantage
- Experience with high-content image analysis and subsequent data handling (coding skills in MATLAB and/or R are considered as assets)
- Skills to autonomously conduct data analysis with solid understanding of statistics
- Excellent written and oral communication skills in English with proven experience in the writing of grants and scientific publications
- Excellent team-working, interpersonal skills, and ability to collaborate with local and international partners
- Enthusiasm and commitment to research
- Ability to think ahead as well as to troubleshoot

**Here’s what awaits you at the LCSB...**:

- **Excellent work environment** with state-of-the-art infrastructure, laboratory and administrative support
- **Truly connected. **We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab - the Scienteens Lab - to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science
- **Be part of a multicultural team. **At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more