Post-doctoral Researcher: Personalized Medicine
il y a 3 semaines
**Post-doctoral researcher: Personalized Medicine Acceleration through Rapid Omics Profiling**:
- Employer- Luxembourg Institute of Health (LIH)- Location- Luxembourg (LU)- Salary- N/A- Closing date- 25 Mar 2024- Discipline
Computing
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.
The Multi-omics Data Science Group is part of the Department of Cancer Research at LIH. We focus on various modalities of high-throughput molecular data obtained in cancer biology. We aim to integrate corresponding data layers to improve our understanding of cancers and drive better patient stratification and treatment. Dr. Reka Toth, the PI of the project, has expertise in epigenetics, bioinformatics and multi-omics profiling.
**PROJECT**
We are looking for a proactive, agile and committed postdoctoral researcher to join our new project aiming to develop techniques for rapid omics profiling.
Recent studies have uncovered biomarkers at various omics levels. Nonetheless, a substantial limitation of these biomarkers is the time-consuming aspects of sample processing, data acquisition and analysis, and the demand for specialized expertise. A pivotal advancement in translational efforts would require streamlining and enhancing this process. The goal of our project is to establish fast, reliable methods to exploit the recent technological and scientific advances to improve personalized medicine. Therefore, we would like to establish a platform that allows clinicians to get timely results from previously developed multi-omics biomarker panels based on Nanopore barcode sequencing and targeted proteomics. We also aim to establish a cfDNA-based DNA and methylome sequencing method to monitor cancer patients and identify potential relapse before it is possible with traditional imaging methods.
**Scientific contacts**
**KEY ACCOUNTABILITIES**
- Set up the project, manage sample processing
- Conduct wet-lab experiments, optimize biomarker analysis, run cfDNA isolation and sequencing
- Participate in data analysis and model generation - depending on individual agreement
- Publish results in scientific journals and/or file patents if applicable
- Participate in training and international scientific conferences
- Disseminate results to the scientific community and the public Participate in laboratory activities including seminars and interaction with other teams
**KEY SKILLS, EXPERIENCE AND QUALIFICATIONS**
- PhD in molecular/cellular biology/biochemistry or similar, with solid research experience.
- Wet laboratory and analytical skills, experience with next-generation or long-read sequencing.
- Interest in bioinformatics and programming
- Previous experience in bioinformatics, R and/or Python programming will be considered a strong asset
- Scientific creativity and originality, precise perseverance, writing skills, good communication skills
- Language skills: fluent command of English; knowledge of other languages of the European Union is an asset
**IN SHORT**
Contract type: 2-year fixed-term contract
Work hours: Full time
Location: Strassen
Start date: ASAP
Ref: MC/PDPMAROP0124/RT/MODAS
**GENDER EQUALITY**
The LIH is an equal opportunities employer.
We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.The LIH is attentive to gender representation among its leadership staff and aims to eliminate obstacles to the recruitment and promotion of female leaders and their career development.
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