Lab Technician Supporting Cell Culture and Live

The **Luxembourg Centre for Systems Biomedicine (LCSB)** is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and _in silico_. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors.

The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary and together we contribute to science and society.

The University of Luxembourg has the following vacancy at the Luxembourg Centre for Systems Biomedicine (LCSB) - Neuroimmunology group**:Technician focusing on supporting the**cell culture experiments targeting molecular mechanisms of neurodegeneration and neuroinflammation**

**AREA**:Role of immune mechanisms in models of neurodegenerative disease.

**DESCRIPTION**:
The Neuroimmunology group at the LCSB, led by Prof. Michael Heneka, started its activities at LCSB in early 2022. It focuses on the role of immune mechanisms in neurodegenerative diseases, with a particular focus on Alzheimer’s disease. This research group has an immediate opening for a motivated, talented and experienced laboratory technician.

**Your Role...**:

- You will prepare primary neuronal and non-neuronal cell cultures, develop and work with iPSC-derived cell models and, in particular, live cell imaging using light and fluorescence microscopy
- You will use sophisticated live cell imaging protocols for the analysis of intra
- and intercellular transport
- You will support daily lab operations, including ordering lab supplies, sample organization and preparation as well as biomolecular extraction
- Additional tasks represent methods of cellular and molecular biology including but not restricted to the extraction of biomolecules (DNA, RNA, proteins) and related detection methods (FACS, ELISA, Western blot, qPCR)

Important technical competencies and tasks include, but are not limited to:

- Solid knowledge on cell culture techniques including preparation of primary cell cultures, iPSCs
- Live cell imaging skills, microscopy
- Troubleshooting of technical problems in sample preparation and extraction workflows
- Experience with standard techniques of molecular biology (FACS, ELISA; Western blot, qPCR)
- Thorough record keeping in a well-organized lab notebook

For further information, please contact:
Prof. Michael Heneka
Telephone: (+352) 46 66 44 6922

**What we expect from you**:

- A Bachelor or Master degree (or equivalent) with wet-lab experience, preferably in primary and iPSC cell culture and with live cell imaging
- Highly reliable and precise working style
- Good organizational skills and ability to work independently
- Basic computer skills to ensure electronic record keeping and generation of work summaries, e.g., documenting quality and quantity results from different protocols
- Experience with various imaging techniques would be an asset
- Attention to detail, especially accurate data entry and sample handling
- Communication in English is essential, both written and spoken

**Here’s what awaits you at the LCSB...**:

- **Excellent work environment** with state-of-the-art infrastructure, laboratory and administrative support
- **Truly connected. **We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab - the Scienteens Lab - to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science
- **Be part of a multicultural team. **At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more