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Postdoctoral Fellow in Human Immunology and

il y a 3 semaines


EschsurAlzette, Luxembourg Luxembourg Institute of Health Temps plein

Funded as a PPP Healthtech project, Dr. Christiane Hilger, Research Group “Molecular and Translational Allergology” at the Department of Infection and Immunity is seeking a** **Post-Doctoral fellow in Human Immunology and Allergic Diseases.**

**Background**

**Project**

Ticks bearing pathogens can transmit infectious diseases such as Lyme borreliosis, tick-borne encephalitis and others. Recently, a non-infectious human disease, namely the alpha-gal syndrome (AGS), was shown to be of tick origin. AGS is characterized by the presence of IgE antibodies directed against the carbohydrate galactose-α-1,3-galactose (alpha-gal or α-gal) and a delayed reaction upon ingestion of mammalian meat. However, not every tick bite will lead to sensitization and it is still not understood how the initial events after a tick bite will either lead to a short-lived natural inflammatory immune reaction or shift the immune response to an uncontrolled Th2 response and the production of specific IgE antibodies that potentially lead to allergic symptoms.

The Postdoctoral Researcher will participate in a translational research study led by Dr. Christiane Hilger (PI of the project) and integrate into a motivated team of international students and scientists at LIH.

**Key Accountabilities**
- Plan, direct, and conduct specialized research experiments to understand immunological mechanism in the context of innate and adaptive immunity;
- Develop and coordinate flow cytometry experiments and perform multi-omic data analysis;
- Collaborate with study partners to achieve research goals;
- Prepare manuscripts for publication in peer-reviewed journals;
- Present research findings at national and international conferences;
- Train and co-supervise under
- and post-graduate students.

**Key Skills, Demonstrated Experience and Qualifications**
- PhD in Biomedical Sciences, Immunology, or related field (ideally completed within the last 3 years);
- Experience with human biosamples, immunoassays and multicolor flow cytometry;
- Strong background and publication record in allergy and/or human immunology (at least one first-author original publication in recognized international journal(s));
- Strong written and oral communication skills in English;
- Desired skills: experience with analyzing multidimensional immune data.

**For any further information please visit**:
**Applications including a motivation letter and a CV should be sent before **_31 January 2025_**. Please indicate your earliest availability in your CV and/or motivation letter.**

**Gender Equality**

The LIH is an equal opportunities employer. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

The LIH is attentive to gender representation among its leadership staff and aims to eliminate obstacles to the recruitment and promotion of female leaders and their career development.

**In Short...**:

- Contract type : Fixed-term contract (CDD)
- Contract duration : 36 months
- Work hours : 40h/week
- Location : rue Henri Koch 29 - 4354 Esch-sur-Alzette
- Start date : 01/04/2025
- Ref : MC/PDHIA1224/CH/ALL2

**How to apply**:
Applications including a letter detailing your motivation and a curriculum vitae should be sent through our website.