Postdoc in Applied Mathematics and Data Analysis
il y a 2 semaines
Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg.
We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and _in silico_.
We focus on neurodegenerative processes and are especially interested in Alzheimer's and Parkinson's disease and their contributing factors.
The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB.
Your Role
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The Systems Control Group seeks a highly skilled Postdoctoral Research Associate. Postdocs are expected to interact with the rest of the group, especially with PhD students and support grant writing.
The open position in part of a JPND project, funded by FNR.
The project aims to enhance the outcome of Deep Brain Stimulation (DBS) in Parkinson's disease (PD) through the individualization and optimization of stimulation settings.
Our vision is to replace the current practice of selecting stimulation pulse width, amplitude, and frequency by trial and error with a model-based patient- specific calculation. This will be achieved by incorporating insights from novel clinical studies into individualized mathematical models underpinning clinically relevant DBS programming tools. The consortium is composed of neurologists, electrical and control engineers, computer scientists, movement scientists, and neurosurgeons from four European countries.
Using arange of mathematical tools, this project aims to improve our understanding of how DBS affects the brain.
It combines all available datasets in the project to create models capturing patient-specific and personalized brain dynamics before and after DBS stimulation.
Models will capture stimulation at a wide range of frequencies, pulse widths and amplitudes across different contact configurations. Data includes EEG, peripheral sensors (such as accelerometers), LFPs and clinical data. Changing stimulation parameters will give us a nonlinear view of changes in brain connections.This will build new hypotheses on the effect of DBS stimulation on different areas of the brain and help us predict effective stimulation parameters.
More details can be found hereWhat we expect from you:
Here's what awaits you at the LCSB
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Excellent work environment with state-of-the-art infrastructure, laboratory and administrative support
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Truly connected. We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab - the Scienteens Lab - to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society's needs and share our passion for science
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Be part of a multicultural team. At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more
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